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Buck Scientific, USA

UHPLC / HPLC System

Model: 8000 Series
Buck Scientific 8000 Series UHPLC/HPLC System

Key Features

  • Dual Drive Design: the binary gradient pump’s dual-plunger drive lowers pressure pulsation for better baseline and retention-time stability
  • Automatic Real-Time Compression Factor Compensation: corrects flow-rate variations caused by different solvent compression factors after high-pressure gradient mixing, for both HPLC and UHPLC analysis
  • Intelligent Mobile Phase Weighing Tray (optional): real-time monitoring and alerts for mobile phase consumption
  • Visualized Sampler Window & Automated Sample Tray Recognition: lets you observe sampling status directly and eliminates tray misalignment
  • Cooling Auto Sampler with configurable multi-channel needle cleaning: keeps biological samples fresh while minimizing cross-contamination and sample loss
  • One-button auto sample compartment door and mobile phase pre-heating for consistent, repeatable results

Core Advantages

Every module of the 8000 Series is engineered for automated, unattended operation with minimal manual intervention.

High-Pressure Binary Gradient Pump

Includes a solvent selection valve and fully automated, software-controlled operation. Seal wash improves salt tolerance and extends plunger and seal lifespan.

Wide-Range Column Oven

Distributed heating and Peltier cooling cover a broad temperature range with high stability, and support multiple valves for automated dual- or multi-column switching.

High-Precision Autosampler

Accommodates multiple sample plates for high-throughput work. Needle-loading injection eliminates cross-contamination with zero sample loss, and sample compartment cooling preserves freshness.

Horizontal Column Oven

Wide temperature range for excellent separation and reproducibility, with active mobile-phase pre-heating for temperature accuracy and stability.

Optional Smart Weighing Tray

Accurately tracks solvent usage in real time, so mobile phase never runs out mid-run.

Quick-Connect Columns

Tool-free, quick-connect fittings make changing columns fast and convenient.

Performance & Detector Compatibility

One platform, matched to whichever detection method your method requires.

Detector Compatibility

UV PDA FLD RID ELSD MS/MS Triple Quadrupole

Reproducibility Data

MetricResult
Retention time reproducibility (30 caffeine injections)0.039% RSD
Peak area reproducibility (30 caffeine injections)0.107% RSD
Peak height reproducibility (30 caffeine injections)0.283% RSD
Online mixed-sample retention time deviation (9 injections)0.068% RSD
Online mixed-sample peak area reproducibility (9 injections)0.1294% RSD

A dual-injector configuration switches automatically between large-volume and low-volume injection methods — in one fast-analysis case this cut a 78-minute reference method down to 8.89 minutes, saving around 70 minutes per run. The platform is in active use across 30+ laboratories running upward of 50,000 tests a year, including top results in national police anti-drug department narcotics-analysis contests.

Application

Professional, customizable solutions for fast, high-throughput HPLC analysis — available in High-Throughput and Online SPE system configurations.

Academic Research

Method development, synthetic biology and strain-screening workflows

Pharmaceutical

Assay, impurity and stability analysis with audit-ready reporting

Biopharmaceutical

Two-dimensional chromatography and biomolecule characterization

Environmental

Trace-level contaminant testing across water, soil and air samples

Forensic

Narcotics and toxicology analysis for government law enforcement laboratories

HPLC Software

An English-language graphical interface gives real-time monitoring of analysis status, and continuously tracks and checks the condition of replaceable parts. Full audit trails and electronic signatures support 21 CFR Part 11 and FDA compliance, with easy import and export of methods for data management.

Flexible, automatically generated report templates keep documentation consistent across pharmaceutical, biotech, environmental and forensic workflows.

Compliance & Data Management

Interface
English graphical interface software with real-time status monitoring
Regulatory compliance
Full audit trails and electronic signatures for 21 CFR Part 11 and FDA compliance
Reporting
Flexible, automatically generated report templates with easy method import/export

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